Proceedings of the 4th International Conference on Innovations in Automation and Mechatronics Engineering (ICIAME2018)

The Mechatronics Department (Accredited by National Board of Accreditation, New Delhi, India) of the G H Patel College of Engineering and Technology, Gujarat, India arranged the 4th International Conference on Innovations in Automation and Mechatronics Engineering 2018, (ICIAME 2018) on 2-3 February 2018. The papers presented during the conference were based on Automation, Optimization, Computer Aided Design and Manufacturing, Nanotechnology, Solar Energy etc and are featured in this book

An experimental investigation of tool nose radius and machining parameters on TI-6AL-4V (ELI) using grey relational analysis, regression and ANN models

Ti-6Al-4V Extra Low Interstitial (ELI) exhibits superior properties because of controlled interstitial element of iron and oxygen. The effects of four cutting parameters namely cutting speed, feed, depth of cut and tool nose radius on responses like cutting force, average cutting temperature and surface roughness have been investigated for turning of Ti-6Al-4V (ELI). Total 81 experiments have been performed in dry environment. Grey Relational Analysis has been used for multi-objective optimization. Analysis of Variance test has been carried out to investigate contribution of input parameters. The model was found fit with R-Square value of 88.74%. Regression and ANN models are developed for prediction and compared. From the Grey relational analysis, it is clear that optimum parameters to minimize cutting force, cutting temperature and surface roughness while turning Ti-6Al-4V (ELI), are cutting speed as 140 rpm, Nose radius 1.2mm, Feed 0.051mm/rev and depth of cut is 0.5mm. In comparison of regression model, the ANN model is found to be more accurate with average error of 3.57%

Protective action of taurine, given as a pretreatment or as a posttreatment, against endotoxin-induced acute lung inflammation in hamsters

To assess the effect of taurine on lipopolysaccharide (LPS)-induced lung inflammation, oxidative stress and apoptosis, female Golden Syrian hamsters were intratracheally instilled with bacterial LPS (0.02 mg in phosphate buffered saline (PBS) pH 7.4), before or after a 3-day intraperitoneal treatment with a single dose of taurine (50 mg/kg/day in PBS pH 7.4), and bronchoalveolar lavage fluid (BALF) and lung tissue samples were collected at 24 hr after the last treatment. In comparison to BALF samples from animals receiving only PBS pH 7.4, and serving as controls, those of LPS-stimulated animals exhibited a higher count of both total leukocytes and neutrophils and increased expression of tumor necrosis factor receptor 1. In comparison to lungs from control animals, those from LPS-treated animals showed increased cellular apoptosis, lipid peroxidation, decreased glutathione levels, altered activities of antioxidant enzymes (catalase, glutathione peroxidase, superoxide dismutase) and focal inflammation confined to the parenchyma. A treatment with taurine was found to significantly attenuate all these alterations, with the protection being, in all instances, greater when given before rather than after LPS. The present results suggest that taurine is endowed with antiinflammatory and antioxidant properties that are protective in the lung against the deleterious actions of Gram negative bacterial endotoxin